There are many resources which you will find on the internet and elsewhere on how to set up your DSLR (digital single lens reflex) camera for wildlife and birds in flight photography, but here is my take on it...
I will walk you through my general camera setup of my Canon 7D, but most of the settings can be found on any DSLR and is not limited to the "big" brands like Canon or Nikon, although the latter two brands' settings are very similar.
Needless to say, every camera brand and model have different settings to fine-tune it even further to your needs and as such I repeat what I have stated to many people before: Know your camera's user manual from the first page to the last!
SHOOTING / EXPOSURE MODES
The most important and generally used shooting modes are shutter priority ("Tv" on Canon and "S" on a Nikon), aperture priority ("Av" on a Canon and "A" on a Nikon) and of course manual mode ("M" on both Canon and Nikon).
I prefer aperture priority mode 90% of the time. The reason for this is simple: I can control the depth of field required for every specific scene I wish to capture. I will for example set my camera to a very general F5.6 when I get into a vehicle at the beginning of a game drive and if it is in the very low light of the early morning, even to the lowest my lens allows, which is for example F4 with my 500mm L lens.